Theory of a reconstructive structural transformation in capsids of icosahedral viruses
S. B. Rochal and V. L. Lorman
A theory of a reconstructive structural transformation in icosahedral capsid shells is developed for a whole family of virulent human viruses. It is shown that the reversible rearrangement of proteins during the virus maturation transformation is driven by the variation in the wave number l associat ... [Phys. Rev. E 80, 051905 (2009)] published Fri Nov 6, 2009.
Dynamical activities of primary somatosensory cortices studied by magnetoencephalography
Kuniharu Kishida
A blind identification method of transfer functions in feedback systems is introduced for examination of dynamical activities of cortices by magnetoencephalography study. Somatosensory activities are examined in 5 Hz periodical median nerve stimulus. In the present paper, we will try two careful pre ... [Phys. Rev. E 80, 051906 (2009)] published Fri Nov 6, 2009.
Generalized Yvon-Born-Green Theory for Molecular Systems
J. W. Mullinax and W. G. Noid
We employ a basis set representation for classical force fields to derive an original system of exact integral equations relating each mode in the force field to an associated set of structural correlation functions. This generalized Yvon-Born-Green theory provides a framework for interpreting compl ... [Phys. Rev. Lett. 103, 198104 (2009)] published Fri Nov 6, 2009.
Extended Kalman filter estimates the contour length of a protein in single molecule atomic force microscopy experiments
Vicente I. Fernandez, Pallav Kosuri, Vicente Parot, and Julio M. Fernandez
Atomic force microscopy force spectroscopy has become a powerful biophysical technique for probing the dynamics of proteins at the single molecule level. Extending a polyprotein at constant velocity produces the now familiar sawtooth pattern force-length relationship. Customarily, manual fits of the ... [Rev. Sci. Instrum. 80, 113104 (2009)] published Fri Nov 6, 2009.
The myth of the 50-50 breast
M. J. Yaffe, J. M. Boone, N. Packard, O. Alonzo-Proulx, S.-Y. Huang et al.
Evaluation of similarity measures for use in the intensity-based rigid 2D-3D registration for patient positioning in radiotherapy
Jian Wu, Minho Kim, Jorg Peters, Heeteak Chung, and Sanjiv S. Samant
Tissue equivalency of phantom materials for neutron dosimetry in proton therapy
Stephen Dowdell, Ben Clasie, Andrew Wroe, Susanna Guatelli, Peter Metcalfe et al.
Geometric feature-based multimodal image registration of contrast-enhanced cardiac CT with gated myocardial perfusion SPECT
Jonghye Woo, Piotr J. Slomka, Damini Dey, Victor Y. Cheng, Byung-Woo Hong et al.
An integral quality monitoring system for real-time verification of intensity modulated radiation therapy
Mohammad K. Islam, Bernhard D. Norrlinger, Jason R. Smale, Robert K. Heaton, Duncan Galbraith et al.
Cumulative sum quality control for calibrated breast density measurements
John J. Heine, Ke Cao, and Craig Beam
Design and construction of a quality control phantom for SPECT and PET imaging
Dylan Christopher Hunt, Harry Easton, and Curtis B. Caldwell
Fast, accurate photon beam accelerator modeling using BEAMnrc: A systematic investigation of efficiency enhancing methods and cross-section data
Margarida Fragoso, Iwan Kawrakow, Bruce A. Faddegon, Timothy D. Solberg, and Indrin J. Chetty
Functional representation of tissue phantom ratios for photon fields
Otto A. Sauer and J. Wilbert
Identification of breast calcification using magnetic resonance imaging
Ali Fatemi-Ardekani, Colm Boylan, and Michael D. Noseworthy
Radiation departments should be certified to provide certain new technologies such as IGRT
Christopher F. Njeh, Abdul Rashid, and Colin G. Orton
Abstract not available. [Med. Phys. 36, 5377 (2009)] published Thu Nov 5, 2009.
Effect of intrinsic curvature on semiflexible polymers
Surya K. Ghosh, Kulveer Singh, and Anirban Sain
Recently many important biopolymers have been found to possess intrinsic curvature. Tubulin protofilaments in animal cells, FtsZ filaments in bacteria and double stranded DNA are examples. We examine how intrinsic curvature influences the conformational statistics of such polymers. We give exact res ... [Phys. Rev. E 80, 051904 (2009)] published Thu Nov 5, 2009.
Generating variable birdsong syllable sequences with branching chain networks in avian premotor nucleus HVC
Dezhe Z. Jin
Songs of songbird species such as Bengalese finch consist of sequences of syllables. While syllables are temporally stereotypical, syllable sequences can vary and follow complex, probabilistic transition rules. Recent experiments and computational models suggest that a syllable is encoded in a chain ... [Phys. Rev. E 80, 051902 (2009)] published Thu Nov 5, 2009.
Soft X-Ray Diffraction Microscopy of a Frozen Hydrated Yeast Cell
Xiaojing Huang, Johanna Nelson, Janos Kirz, Enju Lima, Stefano Marchesini et al.
We report the first image of an intact, frozen hydrated eukaryotic cell using x-ray diffraction microscopy, or coherent x-ray diffraction imaging. By plunge freezing the specimen in liquid ethane and maintaining it below -170 degrees C, artifacts due to dehydration, ice crystallization, and radiati ... [Phys. Rev. Lett. 103, 198101 (2009)] published Thu Nov 5, 2009.
Cryogenic X-Ray Diffraction Microscopy for Biological Samples
Enju Lima, Lutz Wiegart, Petra Pernot, Malcolm Howells, Joanna Timmins et al.
X-ray diffraction microscopy (XDM) is well suited for nondestructive, high-resolution biological imaging, especially for thick samples, with the high penetration power of x rays and without limitations imposed by a lens. We developed nonvacuum, cryogenic (cryo-) XDM with hard x rays at 8 keV and rep ... [Phys. Rev. Lett. 103, 198102 (2009)] published Thu Nov 5, 2009.
Development of Strong Surfaces Using Functionally Graded Composites Inspired by Natural TeethA Theoretical Approach
A. E. Giannakopoulos, A. Kordolemis, and Th. Zisis
In recent years functionally-graded composites have been proposed to develop strong surfaces that can withstand high contact and frictional forces. The present work presents a new graded composite that can be used for the development of surfaces with excellent strength properties. The composite is i ... [J. Eng. Mater. Technol. 132, 011009 (2009)] published Thu Nov 5, 2009.
Physiological fluorescence lifetime imaging microscopy improves Forster resonance energy transfer detection in living cells
Ching-Wei Chang, Mei Wu, Sofia D. Merajver, and Mary-Ann Mycek
Accurate, unambiguous detection of molecular interactions in living cells via measurements of Forster (or fluorescence) resonance energy transfer (FRET) events is experimentally challenging. We develop and apply a physiological fluorescence lifetime imaging microscopy (physiological FLIM) system to ... [J. Biomed. Opt. 14, 060502 (2009)] published Thu Nov 5, 2009.
Charge transport in DNA molecules: Cooperative interplay between the disordered base-pair channel and the ordered backbone
Wei Zhang, Rong Yang, and Sergio E. Ulloa
Charge transport in DNA molecules has raised considerable interest because of its importance in biological processes and potential applications in nanoscale devices. A DNA molecule can be viewed as a quasi-one-dimensional system composed of stacked base pairs (AT, CG) together with backbones of suga ... [Phys. Rev. E 80, 051901 (2009)] published Wed Nov 4, 2009.
Iron Oxide Magnetic Nanotubes and Their Drug Loading and Release Capabilities
Linfeng Chen, Jining Xie, Kiran R. Aatre, and Vijay K. Varadan
Iron oxide magnetic nanomaterials are among the most widely used nanomaterials in nanomedicine. Due to their magnetic and structural properties, iron oxide magnetic nanotubes are extremely attractive for biomedical applications. This paper presents the synthesis of iron oxide magnetic nanotubes, and ... [J. Nanotechnol. Eng. Med. 1, 011009 (2009)] published Wed Nov 4, 2009.
Potassium Ion Sensing With Nanowire Electrodes on a Flexible Substrate for Early Detection of Myocardial Ischemia
Vasuda Ramachandran, Hargsoon Yoon, and Vijay K. Varadan
An increase in extracellular potassium levels is a physiological sign of myocardial ischemia and timely sensing with an implantable potassium sensing biosensor could play a significant role in detecting and expediting care. In this paper, unique fabrication techniques for both planar and nanowire st ... [J. Nanotechnol. Eng. Med. 1, 011008 (2009)] published Wed Nov 4, 2009.
Analysis Techniques for Congruence of the Patellofemoral Joint
K. D. Connolly, J. L. Ronsky, L. M. Westover, J. C. Kupper, and R. Frayne
Quantifying joint congruence may help to understand the relationship between joint function and health. In previous studies, a congruence index (CI) has been used to define subject-specific joint congruence. However, the sensitivity of the CI algorithm to surface representation was unknown. The purp ... [J. Biomech. Eng. 131, 124503 (2009)] published Wed Nov 4, 2009.
Ground Reaction Forces and Lower Extremity Kinematics When Running With Suppressed Arm Swing
Ross H. Miller, Graham E. Caldwell, Richard E. A. Van Emmerik, Brian R. Umberger, and Joseph Hamill
The role of arm swing in running has been minimally described, and the contributions of arm motion to lower extremity joint kinematics and external force generation are unknown. These contributions may have implications in the design of musculoskeletal models for computer simulations of running, sin ... [J. Biomech. Eng. 131, 124502 (2009)] published Wed Nov 4, 2009.
Differences in Aortic Arch Geometry, Hemodynamics, and Plaque Patterns Between C57BL/6 and 129/SvEv Mice
Hui Zhu, Ji Zhang, Jessica Shih, Federico Lopez-Bertoni, John R. Hagaman et al.
Atherosclerotic plaques are distributed differently in the aortic arches of C57BL/6 (B6) and 129/SvEv (129) apolipoprotein E (apoE)-deficient mice. It is now recognized that hemodynamic wall shear stress (WSS) plays an important role in the localization of atherosclerotic development. Since the bloo ... [J. Biomech. Eng. 131, 121005 (2009)] published Wed Nov 4, 2009.
Design and evaluation of a fast Fourier transform-based nonlinear dielectric spectrometer
Ernesto F. Treo and Carmelo J. Felice
Nonlinear dielectric spectroscopy of micro-organism is carried out by applying a moderate electrical field to an aqueous sample through two metal electrodes. Several ad hoc nonlinear spectrometers were proposed in the literature. However, these designs barely compensated the nonlinear distortion der ... [Rev. Sci. Instrum. 80, 114301 (2009)] published Wed Nov 4, 2009.
Intracellular particle tracking as a tool for tumor cell characterization
Yixuan Li, Juergen Schnekenburger, and Michael H. G. Duits
We studied the dynamics of two types of intracellular probe particles, ballistically injected latex spheres and endogenous granules, in tumor cell lines of differerent metastatic potential: breast tumor cells (MCF-7 malignant, MCF-10A benign) and pancreas adenocarcinoma (PaTu8988T malignant, PaTu898 ... [J. Biomed. Opt. 14, 064005 (2009)] published Wed Nov 4, 2009.
Quantitative characterization of optical and physiological parameters in normal breasts using time-resolved spectroscopy: in vivo results of 19 Singapore women
Weirong Mo, Tryphena S. S. Chan, Ling Chen, and Nanguang Chen
We report the quantitative measurements of optical and physiological parameters of normal breasts from 19 Singapore women by using time-resolved diffuse optical spectroscopy. Intrinsic absorption coefficient ([mu]) and reduced scattering coefficients ([mu]) of breasts were calculated from the time-r ... [J. Biomed. Opt. 14, 064004 (2009)] published Wed Nov 4, 2009.
Quantitative three-dimensional photoacoustic tomography of the finger joints: an in vivo study
Yao Sun, Eric Sobel, and Huabei Jiang
We present for the first time in vivo full three-dimensional (3-D) photoacoustic tomography (PAT) of the distal interphalangeal joint in a human subject. Both absorbed energy density and absorption coefficient images of the joint are quantitatively obtained using our finite-element-based photoacoust ... [J. Biomed. Opt. 14, 064002 (2009)] published Wed Nov 4, 2009.
Phytic Acid-Based Layer-by-Layer Assembly for Fabrication of Mesoporous Gold Film and Its Biosensor Application
Yao Wang, Xiaoling Ma, Ying Wen, Yaqing Zheng, Guoping Duan et al.
Phytic acid was introduced as a binder to construct a controllable structure at an electrode surface. In this paper, phytic acid and gold nanoparticles were assembled onto the surface of a gold electrode layer-by-layer to form a three-dimensional mesoporous gold interface. Then, a high sensitive hor ... [J. Electrochem. Soc. 157, K5 (2009)] published Tue Nov 3, 2009.
Looking Back, Looking Ahead
Bruce J. Tromberg
Abstract not available. [J. Biomed. Opt. 14, 050101 (2009)] published Tue Nov 3, 2009.
Monodisperse self-assembly in a model with protein-like interactions
Alex W. Wilber, Jonathan P. K. Doye, Ard A. Louis, and Anna C. F. Lewis
We study the self-assembly behavior of patchy particles with proteinlike interactions that can be considered as a minimal model for the assembly of viral capsids and other shell-like protein complexes. We thoroughly explore the thermodynamics and dynamics of self-assembly as a function of the parame ... [J. Chem. Phys. 131, 175102 (2009)] published Mon Nov 2, 2009.
A global mathematical investigation of a predator-prey model. (arXiv:0911.1007v1 [math.DS])
ePrint arXiv http://arXiv.org/
Cooperativity and Frustration in Protein-Mediated Parallel Actin Bundles. (arXiv:0911.1064v2 [cond-mat.soft])
ePrint arXiv http://arXiv.org/
Using profiles based on hydropathy properties to define essential regions for splicing. (arXiv:0911.1066v1 [q-bio.QM])
ePrint arXiv http://arXiv.org/
A Fast Algorithm for Computing Geodesic Distances in Tree Space. (arXiv:0907.3942v2 [q-bio.PE] UPDATED)
ePrint arXiv http://arXiv.org/
Evolutionary Analysis of Biological Excitability. (arXiv:q-bio/0609023v5 [q-bio.BM] UPDATED)
ePrint arXiv http://arXiv.org/
Discontinuous nonequilibrium phase transitions in a nonlinearly pulse-coupled excitable lattice model. (arXiv:0910.5717v1 [nlin.CG] CROSS LISTED)
ePrint arXiv http://arXiv.org/