About DBIS   | Story archive   | Contact DBIS  | DBIS home

Saving Eyes

Ocular Oncologists Inject Drug into Eye to Starve Tumors and Save Sight

January 1, 2008

Ocular oncologists adopted a drug originally intended to treat colon cancer as a treatment for cancers in the eye as well as macular degeneration. The drug reduces abnormal blood vessel growth, which starves tumors and stops blood vessels from leaking. This interrupts the processes that would, if not stopped, greatly damage patients' vision.

read the full story...

Science Insider

ABOUT CANCER IN THE EYE: Ocular melanoma -- eye cancer -- is a particularly rare and aggressive form of cancer that attacks the pigment cells in the retina. There are essentially two types of intraocular melanoma: low-grade tumors, which grow slowly and rarely metastasize, and high-grade tumors, which grow more quickly and metastasize at a very early stage. Once a tumor metastasizes, the cancer spreads quickly to the liver and other organs, and a patient has only 6 to 12 months to live in the worst cases, although some can survive for as long as 5 years. The National Eye Institute estimates some 2,000 newly diagnosed cases of ocular melanoma occur per year in the United States and Canada --roughly seven in one million people. It affects people of all ages and races, and is not hereditary. Ocular melanoma kills nearly half of those who develop it.

ABOUT THE RETINA: We can see because light reflects off objects in our surroundings and enters the eye through the pupil. The light is then focused and inverted by the cornea and the lens, and projected onto the back of the eye. There we find the retina, which is lined with a series of photoreceptors that convert the light signal into an electrical signal. Ganglion cells then transmit those signals to the brain via the optic nerve.

Video help

Latest stories

  • A Satellite Named Violet and a Student Named Amanda
  • Behind the Scenes with the K-Team
  • Deep Space Discoveries
  • Dogs Fighting Cancer
  • Earthquake! What's Your Risk

More information on this story

On The Web: Untreatable Eye Disease Improves With Avastin

To Go Inside This Science:
Axel Bang
Public Affairs for The New York Eye Cancer Center
914-234-5433
aband@axelbang.com


© 2011 American Institute of Physics